Talking to Your Doctor About New or Ongoing Symptoms Is Important

Talking about your symptoms with your doctor is important for your treatment and a great way to help you get the appropriate care. It can be difficult to remember everything you want to discuss once you get to your visit—that's why it's important to write it down. Be honest and open when talking about symptoms with your doctor, regardless of how big or small they may be. This will help your doctor get a better idea of what's going on and to help you get the most appropriate treatment possible.

To help you start the conversation with your doctor, we put together this quick and easy questionnaire.

Answer the questions below, and when you're finished with the questionnaire, save it to your phone or print it. Then, bring it to your next appointment and share it with your doctor. This will help them better understand your symptoms and the impact they are having on you.

Important Safety Information about ENTYVIO^® (vedolizumab)

Do not receive ENTYVIO if you have had an allergic reaction to ENTYVIO or any of its ingredients.
ENTYVIO may cause serious side effects, including:
- Infusion-related and serious allergic reactions can happen while you are receiving ENTYVIO or several hours after treatment. You may need treatment if you have an allergic reaction. Tell your healthcare provider or get immediate medical help if you get any of these symptoms during or after an infusion of ENTYVIO: rash, itching, swelling of your lips, tongue, throat or face, shortness of breath or trouble breathing, wheezing, dizziness, feeling hot, or palpitations (feel like your heart is racing).
- ENTYVIO may increase your risk of getting a serious infection. Before receiving and during treatment with ENTYVIO, tell your healthcare provider if you think you have an infection or symptoms of an infection, such as fever, chills, muscle aches, cough, shortness of breath, runny nose, sore throat, red or painful skin or sores on your body, tiredness, or pain during urination.
- People with weakened immune systems can get progressive multifocal leukoencephalopathy (PML) (a rare, serious brain infection caused by a virus). Although unlikely while receiving ENTYVIO, a risk of PML cannot be ruled out. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML. Tell your healthcare provider right away if you have any of the following symptoms: confusion or problems thinking, loss of balance, change in the way you walk or talk, decreased strength or weakness on one side of the body, blurred vision, or loss of vision.
- Liver problems can happen in people who receive ENTYVIO. Tell your healthcare provider right away if you have any of the following symptoms: tiredness, loss of appetite, pain on the right side of your abdomen, dark urine, or yellowing of the skin and eyes (jaundice).
The most common side effects of ENTYVIO include common cold, headache, joint pain, nausea, fever, infections of the nose and throat, tiredness, cough, bronchitis, flu, back pain, rash, itching, sinus infection, throat pain, and pain in extremities. These are not all the possible side effects of ENTYVIO. Call your healthcare provider for medical advice about side effects.
Before receiving ENTYVIO, tell your healthcare provider about all of your medical conditions, including if you: have or think you may have an infection or have infections that keep coming back; have liver problems; have tuberculosis (TB) or have been in close contact with someone with TB; have recently received or are scheduled to receive a vaccine; or if you are pregnant, breastfeeding, plan to become pregnant, or plan to breastfeed.

Please see the full Prescribing Information, including the Medication Guide, for ENTYVIO and talk with your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Uses of ENTYVIO^® (vedolizumab)

ENTYVIO is a prescription medicine used in adults for the treatment of:

moderately to severely active ulcerative colitis
moderately to severely active Crohn’s disease

Important Safety Information about ENTYVIO^® (vedolizumab)

Do not receive ENTYVIO if you have had an allergic reaction to ENTYVIO or any of its ingredients.
ENTYVIO may cause serious side effects, including:
- Infusion-related and serious allergic reactions can happen while you are receiving ENTYVIO or several hours after treatment. You may need treatment if you have an allergic reaction. Tell your healthcare provider or get immediate medical help if you get any of these symptoms during or after an infusion of ENTYVIO: rash, itching, swelling of your lips, tongue, throat or face, shortness of breath or trouble breathing, wheezing, dizziness, feeling hot, or palpitations (feel like your heart is racing).
- ENTYVIO may increase your risk of getting a serious infection. Before receiving and during treatment with ENTYVIO, tell your healthcare provider if you think you have an infection or symptoms of an infection, such as fever, chills, muscle aches, cough, shortness of breath, runny nose, sore throat, red or painful skin or sores on your body, tiredness, or pain during urination.
- People with weakened immune systems can get progressive multifocal leukoencephalopathy (PML) (a rare, serious brain infection caused by a virus). Although unlikely while receiving ENTYVIO, a risk of PML cannot be ruled out. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML. Tell your healthcare provider right away if you have any of the following symptoms: confusion or problems thinking, loss of balance, change in the way you walk or talk, decreased strength or weakness on one side of the body, blurred vision, or loss of vision.
- Liver problems can happen in people who receive ENTYVIO. Tell your healthcare provider right away if you have any of the following symptoms: tiredness, loss of appetite, pain on the right side of your abdomen, dark urine, or yellowing of the skin and eyes (jaundice).
The most common side effects of ENTYVIO include common cold, headache, joint pain, nausea, fever, infections of the nose and throat, tiredness, cough, bronchitis, flu, back pain, rash, itching, sinus infection, throat pain, and pain in extremities. These are not all the possible side effects of ENTYVIO. Call your healthcare provider for medical advice about side effects.
Before receiving ENTYVIO, tell your healthcare provider about all of your medical conditions, including if you: have or think you may have an infection or have infections that keep coming back; have liver problems; have tuberculosis (TB) or have been in close contact with someone with TB; have recently received or are scheduled to receive a vaccine; or if you are pregnant, breastfeeding, plan to become pregnant, or plan to breastfeed.

Please see the full Prescribing Information, including the Medication Guide, for ENTYVIO and talk with your healthcare provider.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Uses of ENTYVIO^® (vedolizumab)

ENTYVIO is a prescription medicine used in adults for the treatment of:

moderately to severely active ulcerative colitis
moderately to severely active Crohn’s disease

Note & Discuss Your Symptoms

How many times have you had to refill your prescription of steroids in the last year?
(Question 1 of 6)

How often do you currently take steroids to control flare-ups, as prescribed by your doctor?
(Question 2 of 6)

How many bowel movements do you have a day?
(Question 3 of 6)

These could be common symptoms of ulcerative colitis (UC) or Crohn's disease (CD): how often do you experience any of the following symptoms?
(Question 4 of 6)

Please indicate how you feel using the following scale:
(Question 5 of 6)

Are your current treatments working well enough?
(Question 6 of 6)

Congratulations!

Note & Discuss Your Symptoms

Talking to Your Doctor About New or Ongoing Symptoms Is Important

How many times have you had to refill your prescription of steroids in the last year? (Question 1 of 6)

How often do you currently take steroids to control flare-ups, as prescribed by your doctor? (Question 2 of 6)

How many bowel movements do you have a day? (Question 3 of 6)

These could be common symptoms of ulcerative colitis (UC) or Crohn's disease (CD): how often do you experience any of the following symptoms? (Question 4 of 6)

Please indicate how you feel using the following scale: (Question 5 of 6)

Are your current treatments working well enough? (Question 6 of 6)