The true causes of Crohn's disease are not completely understood. What we do know is that if you or a close relative have the disease, your family members may be at an increased chance of Crohn's. Researchers believe that a combination of hereditary, genetic, and/or environmental factors may contribute to the development of Crohn's disease. Diet and stress may aggravate Crohn's disease, but they do not cause the disease on their own.
Crohn's disease is the result of an abnormal immune system response, during which your body mistakes certain bacteria and other materials in the intestine for foreign or invading substances. It then sends white blood cells into the intestines, where they create inflammation. Normally, this would cause a temporary inflammation that would resolve itself. But with Crohn's disease, researchers believe that once your immune system is "turned on," it doesn't know how to "properly turn off." As a result, chronic inflammation damages the intestine and causes the symptoms of Crohn's disease.
Crohn's disease is a chronic disease, and some patients may experience worsening of the disease over time.
It's important to understand how your condition is affecting you so you can explain it to your doctor. Use the doctor discussion guide to help you prepare for your discussion with your doctor.
The links to third-party websites contained on this website are provided solely for your convenience. Takeda does not control the content contained on any third-party website linked from this website. Your activities at those websites will be governed by the policies and practices of those third parties.
Please select "Continue" if you wish to be taken to this third-party website.Cancel Continue