For adults with moderate to severe Crohn’s disease.

#1 prescribed biologic for Crohn's and ulcerative colitis combined.

†Quarterly analysis of claims data from January 2023–December 2025.

Discover the only gut-focused treatment* for Crohn’s

that works right where U need it

*ENTYVIO helps block certain inflammation-causing cells from entering the gut.

Focus U Want

Helps block inflammation right where it occurs: In your gut

ENTYVIO helps block certain inflammation-causing cells from entering the gut.

Results U Need

Lasting relief and steroid-free remission for Crohn’s disease after 1 year†


Some people with Crohn’s experienced rapid symptom relief as early as 6 weeks†

Individual results may vary.

†Many patients taking ENTYVIO IV achieved remission at Week 52, some without steroids. Some achieved visible improvement of the gut lining and remission at Week 6. Remission is a measure to determine when a patient with Crohn’s or UC is experiencing few to no symptoms and an improvement in their condition.

Experience U Expect

Backed by 26 years of combined clinical research‡


Prescribed to people for more than 12 years


Proven safety record across clinical trials§

§Evaluated safety vs placebo in more than 3300 adults (UC, Crohn's, and healthy volunteers).

ENTYVIO vial and ENTYVIO Pen.

Support U Deserve

ENTYVIO starting at $0||


Wide coverage through both employer-provided and self‑purchased health insurance plans


Dedicated 1-on-1 support from nurse educators, injection training nurses, and patient mentors

‡Based on a clinical trial of vedolizumab initiated in 2000.

||For eligible patients only. Terms & conditions apply.

Coverage of ENTYVIO as of December 2025.

IV=intravenous.

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Discover ENTYVIO for Crohn's Disease

ENTYVIO (vedolizumab) is a biologic used to treat moderate to severe Crohn’s disease.​

You can explore more about ENTYVIO for Crohn’s—see treatment results, hear from patients with Crohn’s, and learn about support and financial help available to you.