Overview of treatment options for Crohn's disease

ENTYVIO is for adults with moderate to severe Crohn's disease

Patient Portrayal

Conventional treatment options

  • Corticosteroids

    A class of drugs that work to lower the activity of the immune system, thereby decreasing the inflammatory response. They are not typically used long term.

  • Immunomodulators

    A class of drugs that modify the immune system's ability to cause inflammation. They are typically used when corticosteroids don't relieve symptoms.

Advanced therapy options

Advanced therapies are used after conventional therapies.


  • Anti-Integrins
    Anti-α4β7 integrins, such as ENTYVIO, block gut-directed white blood cells involved in the inflammatory response from moving out of the blood vessels and into the gut tissue by blocking a protein on the surface of these cells.
  • Anti-TNFα
    Bind and block a protein called tumor necrosis factor alpha (TNFα), which promotes inflammation in the intestine.
  • Anti-Interleukins
    Block interleukin proteins, which are associated with the inflammation process.

Having a thorough discussion about the benefits and risks of all available medications with your doctor can help you understand what treatments may be appropriate for you.

How ENTYVIO works

Curious how ENTYVIO helps fight Crohn's? Here’s an easy-to-understand description.

See the science