For adults with moderate to severe ulcerative colitis (UC).
†Quarterly analysis of claims data from January 2023–December 2025.
What are the first steps to your treatment?
Though no 2 paths are the same, there are a few key steps that everyone who’s been prescribed ENTYVIO must go through. If you’ve received the Starter Kit, you’re already on your way. Up next is signing up for EntyvioConnect, getting coverage authorization, and scheduling your IV starter doses.
Get coverage authorization
After getting prescribed ENTYVIO, your health insurance provider must approve your coverage for ENTYVIO. These 2 steps
are typically handled by your doctor's office.
After getting prescribed ENTYVIO, your health insurance provider must approve your coverage for ENTYVIO. These 2 steps are typically handled by your doctor's office.
Keep in mind that the authorization process may take several weeks. Your doctor's office will be in touch if they need
additional information. Once your coverage is approved, you'll be ready to receive your starter doses.
Keep in mind that the authorization process may take several weeks. Your doctor's office will be in touch if they need additional information. Once your coverage is approved, you'll be ready to receive your starter doses.
Care Team and Treatment Pathway 101
Throughout your diagnostic journey and pathway to treatment, your care team can help you navigate the experiences ahead. Check out this resource to find more information about the people who can help along the way, the terms you may hear them use, your treatment options, and more.
Sign up for EntyvioConnect
EntyvioConnect is a patient support program designed to help make your journey as stress-free as possible, offering resources and guidance from a caring team of experts, including help navigating insurance processes like coverage authorization and obtaining a co-pay card.
If you’ve been prescribed the ENTYVIO Pen, be sure to ask your Patient Support Manager to send you the self-injection training kit.
This kit has helpful information and resources for people getting started on ENTYVIO, including a universal restroom access card and a printed copy of a treatment map. If you didn't receive your kit when you were prescribed ENTYVIO, talk to your healthcare provider.
What are starter doses like?
Whether you’ve been prescribed intravenous (IV) infusion or the ENTYVIO Pen as maintenance therapy, everyone who starts ENTYVIO will have at least 2 IV starter doses.
Your healthcare provider will administer ENTYVIO as an infusion through a needle placed in a vein in your arm, either at their office, at an infusion center, or in your home. Infusions last approximately 30 minutes. They will also monitor you during and after the infusion to see if you have a reaction to the treatment.
If you haven’t already, reach out to your healthcare provider and make sure your starter doses are scheduled.
Starter Dose Schedule
Depending on which maintenance option you’ve been prescribed, your starter dose schedule may vary.
ENTYVIO IV starting treatment schedule
You will receive ENTYVIO by infusion at Weeks 0, 2, and 6.
ENTYVIO Pen starting treatment schedule
You will receive ENTYVIO by infusion at Weeks 0 and 2.*
*Your healthcare provider will determine if it's appropriate to transition to self-administration with the ENTYVIO Pen after at least 2 IV doses.
Wondering if there’s an infusion center close to home?
Use our infusion center finder to locate one that’s convenient for you.
One ENTYVIO. Two administration options.
Once you’ve received your starter doses of ENTYVIO—always administered through intravenous (IV) infusion—you begin your follow-up doses, known as maintenance doses. You’ll undergo a maintenance evaluation with your healthcare provider to determine which administration option is right for you: IV infusion or self-administered injection under the skin (subcutaneous).
Remember, EntyvioConnect is available to support you throughout this process and answer any questions you might have.
Want to learn more about ENTYVIO and how it works?
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